In 1943 the club (then playing as the Cincinnati Clowns) toned down its clowning routines to become a member of the Negro American League, a league affiliation which it maintained through the end of the Negro Leagues' golden age in 1949 and beyond. Though the club routinely fielded a quality lineup, the Clowns failed to capture an NAL pennant during this period.
After the demise of the Negro National League and integration of organized baseball, the Clowns gradually returned to their clowning routines as a measure of financial
necessity. During the early 1950s the team had the distinction of signing a young Hank Aaron who would, of course, ultimately become baseball's all-time home run king.
The Clowns fielded such stars as Buster Haywood, DeWitt "Woody" Smallwood, showman "Goose" Tatum, and future Major Leaguers John Wyatt (Kansas City Athletics), Paul Casanova (Washington Senators), and Choo-Choo Coleman (New York Mets).
The Clowns were the first professional baseball team to hire a female player. Marcenia "Tony" Stone played second base
with the team in 1953. She batted .267. The following year the Clowns sold her contract to the Kansas City Monarchs. They hired two women replacements: Marie "Peanuts" Johnson, pitcher; and, Connie Morgan, second
base. Women also served as umpires for the team.
After many years of operation as a barnstorming team, the Clowns finally disbanded around 1988.